What was the main conflict known as the war between the North and the South?

The main conflict known as the war between the North and the South is referred to as the Civil War. This war, which lasted from 1861 to 1865, was primarily fought over the issues of slavery and states’ rights. The Northern states, also known as the Union, were against the expansion of slavery, while the Southern states, known as the Confederacy, sought to maintain and expand the institution of slavery. This internal conflict was significant in shaping the future of the United States, ultimately leading to the abolition of slavery and the preservation of the Union.

The other conflicts listed do not pertain specifically to the North-South divide in the context of American history. World War II was a global conflict involving many nations, while the Spanish American War and the Mexican American War were conflicts primarily involving territorial disputes and the expansion of U.S. territories, neither of which specifically addressed the division between Northern and Southern states.